ZFIN is now using GRCz12tu for Genomic Data
Gene
serpine3
- ID
- ZDB-GENE-050309-223
- Name
- serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
- Symbol
- serpine3 Nomenclature History
- Previous Names
-
- im:7152538
- si:ch211-219a4.10
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in Muller cell; brain; retina; and retinal inner nuclear layer. Orthologous to human SERPINE3 (serpin family E member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Indrischek et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023795 | Serpin, conserved site |
| Domain | IPR023796 | Serpin domain |
| Family | IPR000215 | Serpin family |
| Family | IPR031172 | Serpin E3 |
| Homologous_superfamily | IPR036186 | Serpin superfamily |
| Homologous_superfamily | IPR042178 | Serpin superfamily, domain 1 |
| Homologous_superfamily | IPR042185 | Serpin superfamily, domain 2 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Serpin, conserved site | Serpin domain | Serpin E3 | Serpin family | Serpin superfamily | Serpin superfamily, domain 1 | Serpin superfamily, domain 2 |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B0UYL8 | InterPro |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
serpine3-201
(1)
|
Ensembl | 1,863 nt | ||
| ncRNA |
serpine3-002
(1)
|
Ensembl | 885 nt | ||
| ncRNA |
serpine3-003
(1)
|
Ensembl | 905 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers