ZFIN is now using GRCz12tu for Genomic Data
Gene
abcg4a
- ID
- ZDB-GENE-050517-39
- Name
- ATP-binding cassette, sub-family G (WHITE), member 4a
- Symbol
- abcg4a Nomenclature History
- Previous Names
-
- abcg1a (1)
- abcg4
- si:ch211-117m20.3
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ABC-type sterol transporter activity. Predicted to be involved in cholesterol efflux; cholesterol homeostasis; and transmembrane transport. Predicted to be located in endomembrane system and membrane. Predicted to be active in plasma membrane. Is expressed in brain. Orthologous to human ABCG4 (ATP binding cassette subfamily G member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhou et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR013525 | ABC-2 type transporter, transmembrane domain |
| Domain | IPR043926 | ABC transporter family G domain |
| Family | IPR050352 | ATP-binding cassette subfamily G transporters |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ABC-2 type transporter, transmembrane domain | ABC transporter family G domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ATP-binding cassette subfamily G transporters | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A2BFT1 | InterPro | 641 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
abcg4a-202
(1)
|
Ensembl | 2,424 nt | ||
| mRNA |
abcg4a-203
(1)
|
Ensembl | 1,926 nt | ||
| ncRNA |
abcg4a-002
(1)
|
Ensembl | 500 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers