ZFIN is now using GRCz12tu for Genomic Data
Gene
hs6st1a
- ID
- ZDB-GENE-050524-1
- Name
- heparan sulfate 6-O-sulfotransferase 1a
- Symbol
- hs6st1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables heparan sulfate 6-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to act upstream of or within DNA integration and proteolysis. Predicted to be located in membrane. Is expressed in several structures, including immature eye; nervous system; neural keel; neural tube; and polster. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110038 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 15 with or without anosmia | Alliance | {Hypogonadotropic hypogonadism 15 with or without anosmia} | 614880 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase |
|---|---|---|---|---|---|
| UniProtKB:Q56UJ5 | InterPro | 413 | |||
| UniProtKB:A0AB13ABZ8 | InterPro | 413 | |||
| UniProtKB:A0AB32TZX1 | InterPro | 1354 | |||
| UniProtKB:A0AC58GUG1 | InterPro | 248 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hs6st1a-201
(1)
|
Ensembl | 737 nt | ||
| mRNA |
hs6st1a-202
(1)
|
Ensembl | 1,242 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers