dpysl3

ID

ZDB-GENE-050720-2

Name

dihydropyrimidinase like 3

Symbol

dpysl3 Nomenclature History

Previous Names

CRMP-4 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Acts upstream of or within axonogenesis; forebrain development; and regulation of axonogenesis. Predicted to be located in cytoplasm and growth cone. Predicted to be active in cytosol. Is expressed in nervous system; neural plate; spinal cord neural tube; and trigeminal placode. Orthologous to human DPYSL3 (dihydropyrimidinase like 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dpysl3 Human Ortholog

No data available

Associated With dpysl3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006680	Amidohydrolase-related
Family	IPR011778	Hydantoinase/dihydropyrimidinase
Family	IPR050378	Metallo-dependent Hydrolases Superfamily
Homologous_superfamily	IPR011059	Metal-dependent hydrolase, composite domain superfamily
Homologous_superfamily	IPR032466	Metal-dependent hydrolase