ZFIN is now using GRCz12tu for Genomic Data
Gene
dgat2
- ID
- ZDB-GENE-050913-15
- Name
- diacylglycerol O-acyltransferase 2
- Symbol
- dgat2 Nomenclature History
- Previous Names
-
- zgc:113394
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable diacylglycerol O-acyltransferase activity. Acts upstream of or within lipid homeostasis; regulation of response to endoplasmic reticulum stress; and response to (R)-carnitine. Predicted to be located in lipid droplet and perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in female organism; intestine; liver; and male organism. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatotic liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 20 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007130 | Diacylglycerol acyltransferase |
Domain Details Per Protein
| Protein | Additional Resources | Length | Diacylglycerol acyltransferase |
|---|---|---|---|
| UniProtKB:Q4V9F0 | InterPro | 361 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers