ZFIN is now using GRCz12tu for Genomic Data

Gene

pou2f2b

ID

ZDB-GENE-060310-1

Name

POU class 2 homeobox 2b

Symbol

pou2f2b Nomenclature History

Previous Names

Oct2b (1)
im:7141417 (1)
si:ch73-111a8.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in central nervous system; cranial ganglion; and neurons. Orthologous to human POU2F2 (POU class 2 homeobox 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7141417 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou2f2b Human Ortholog

No data available

Associated With pou2f2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeodomain
Domain	IPR013847	POU domain
Family	IPR000972	Octamer-binding transcription factor
Family	IPR050255	POU domain transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M3AHW2	InterPro	680
UniProtKB:A0AB13A990	InterPro	695
UniProtKB:A0AB32T2I9	InterPro	565
UniProtKB:A0AB32T581	InterPro	588
UniProtKB:A0AB32T666	InterPro	685
UniProtKB:A0AB32T6C8	InterPro	679
UniProtKB:A0AB32T7N9	InterPro	620
UniProtKB:A0AB32T9F3	InterPro	578
UniProtKB:A0AB32T9I4	InterPro	571
UniProtKB:A0AB32T9I7	InterPro	613
UniProtKB:A0AB32TB61	InterPro	595
UniProtKB:A0AC58HGN0	InterPro	682
UniProtKB:A0AC58HGN3	InterPro	689
UniProtKB:A0AC58HGN5	InterPro	678
UniProtKB:A0AC58HGN7	InterPro	651
UniProtKB:A0AC58HGN8	InterPro	661
UniProtKB:A0AC58HGN9	InterPro	668
UniProtKB:A0AC58HGP0	InterPro	592
UniProtKB:A0AC58HGP1	InterPro	592
UniProtKB:A0AC58HGP2	InterPro	582
UniProtKB:A0AC58HGP4	InterPro	657
UniProtKB:A0AC58HGP5	InterPro	574
UniProtKB:A0AC58HGP6	InterPro	682
UniProtKB:A0AC58HGP8	InterPro	679
UniProtKB:A0AC58HGP9	InterPro	578
UniProtKB:A0AC58HGQ0	InterPro	568
UniProtKB:A0AC58HGQ2	InterPro	672
UniProtKB:A0AC58HGQ3	InterPro	672
UniProtKB:A0AC58HGQ4	InterPro	550
UniProtKB:A0AC58HGQ5	InterPro	540
UniProtKB:A0AC58HGQ6	InterPro	571
UniProtKB:A0AC58HGQ7	InterPro	557
UniProtKB:A0AC58HGQ8	InterPro	561
UniProtKB:A0AC58HGQ9	InterPro	547
UniProtKB:A0AC58HGR0	InterPro	546
UniProtKB:A0AC58HGR1	InterPro	502
UniProtKB:A0AC58HGR2	InterPro	481
UniProtKB:A0AC58HGR3	InterPro	568
UniProtKB:A0AC58HGR4	InterPro	471
UniProtKB:A0AC58HGR5	InterPro	567
UniProtKB:A0AC58HGR6	InterPro	492
UniProtKB:A0AC58HGR7	InterPro	561
UniProtKB:A0AC58HGR9	InterPro	567
UniProtKB:A0AC58HGS2	InterPro	477
UniProtKB:A0AC58HGS8	InterPro	481
UniProtKB:A0AC58HGT0	InterPro	460
UniProtKB:A0A8M3AQD8	InterPro	703
UniProtKB:A0A8M3AT79	InterPro	710
UniProtKB:A0A8M6YSU9	InterPro	689
UniProtKB:A0A8M6YVD3	InterPro	700
UniProtKB:A0A8M6Z1A5	InterPro	599

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pou2f2a-202 (1) Ensembl	Ensembl	2,309 nt	Select Tool ZFIN BLAST
mRNA	pou2f2a-203 (1) Ensembl	Ensembl	6,951 nt	Select Tool ZFIN BLAST
mRNA	pou2f2b-201 (1) Ensembl	Ensembl	1,389 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations