ZFIN is now using GRCz12tu for Genomic Data
Gene
sall4
- ID
- ZDB-GENE-060328-2
- Name
- spalt-like transcription factor 4
- Symbol
- sall4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables chromatin binding activity. Acts upstream of or within axis elongation involved in somitogenesis; embryonic pectoral fin morphogenesis; and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including brain; fin bud; mesoderm; neural plate; and neural tube. Human ortholog(s) of this gene implicated in Duane retraction syndrome; Duane-radial ray syndrome; Holt-Oram syndrome; IVIC syndrome; and ventricular septal defect. Orthologous to human SALL4 (spalt like transcription factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb372 (18 images)
- cb614 (19 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Duane-radial ray syndrome | Alliance | Duane-radial ray syndrome | 607323 |
| IVIC syndrome | Alliance | ?IVIC syndrome | 147750 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sal C2H2-type zinc-finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
| UniProtKB:A0MWC1 | InterPro | 1091 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers