ZFIN is now using GRCz12tu for Genomic Data
Gene
pdyn
- ID
- ZDB-GENE-060417-1
- Name
- prodynorphin
- Symbol
- pdyn Nomenclature History
- Previous Names
-
- fj38c03
- wu:fj38c03
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables opioid receptor binding activity. Predicted to be involved in neuropeptide signaling pathway and sensory perception of pain. Predicted to act upstream of or within chemical synaptic transmission. Predicted to be located in extracellular region. Predicted to be active in neuronal cell body and neuronal dense core vesicle lumen. Is expressed in brain and hypothalamus. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; amphetamine abuse; drug dependence (multiple); and spinocerebellar ataxia 23. Orthologous to human PDYN (prodynorphin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia 23 | Alliance | Spinocerebellar ataxia 23 | 610245 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Opioid neuropeptide precursor | Proenkephalin B |
|---|---|---|---|---|
| UniProtKB:A0A8M3B6F1 | InterPro | 253 | ||
| UniProtKB:Q6JT77 | InterPro | 252 | ||
| UniProtKB:A0A8M3AYT0 | InterPro | 261 | ||
| UniProtKB:A0AC58IJE1 | InterPro | 253 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers