Gene
tpcn1
- ID
- ZDB-GENE-060526-199
- Name
- two pore segment channel 1
- Symbol
- tpcn1 Nomenclature History
- Previous Names
-
- si:dkey-125i10.5
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable identical protein binding activity and monoatomic cation channel activity. Predicted to be involved in endocytosis involved in viral entry into host cell. Predicted to be located in early endosome membrane; endolysosome; and recycling endosome membrane. Predicted to be active in endosome membrane and lysosomal membrane. Orthologous to human TPCN1 (two pore segment channel 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Rice et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ion transport domain | Two pore channel protein 1 | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BCG3 | InterPro | 810 | |||
| UniProtKB:A0A8N7TFG5 | InterPro | 811 | |||
| UniProtKB:A2BHL7 | InterPro | 805 |
Interactions and Pathways
No data available
Plasmids
No data available