ZFIN is now using GRCz12tu for Genomic Data
Gene

dab1a

ID
ZDB-GENE-060528-1
Name
DAB adaptor protein 1a
Symbol
dab1a Nomenclature History
Previous Names
  • dab1
  • si:dkey-242m13.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be involved in neuron migration. Predicted to act upstream of or within cell differentiation. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; immature eye; pronephric duct; retina; and spinal cord interneuron. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dab1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia 37 Alliance Spinocerebellar ataxia 37 615945
Associated With dab1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048559 Disabled homolog 1/2, sulfatide-binding motif
Domain IPR006020 PTB/PI domain
Domain IPR048561 Disabled, phosphotyrosine-binding domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Disabled homolog 1/2, sulfatide-binding motif Disabled, phosphotyrosine-binding domain PH-like domain superfamily PTB/PI domain
UniProtKB:A0A8M3AKN7 InterPro 571
UniProtKB:A0A8M3AW18 InterPro 597
UniProtKB:A0A8M2BHH7 InterPro 576
UniProtKB:F1Q6J4 InterPro 565
UniProtKB:A2BEF7 InterPro 537
UniProtKB:A0A8M3B3Y8 InterPro 563
UniProtKB:Q1PSH4 InterPro 588
UniProtKB:A0A0R4IQY1 InterPro 586
UniProtKB:A0AB32T8P7 InterPro 576
UniProtKB:A0AB32T9E3 InterPro 558
UniProtKB:A0AB32TEC2 InterPro 545
UniProtKB:A0AC58I4Y5 InterPro 552
UniProtKB:A0AC58I4Y8 InterPro 547
UniProtKB:A0AC58I4Z2 InterPro 532
UniProtKB:A0AC58I4Z3 InterPro 565
UniProtKB:A0AC58I4Z5 InterPro 534
UniProtKB:A0AC58I4Z7 InterPro 537
UniProtKB:A0AC58I4Z8 InterPro 526
UniProtKB:A0AC58I4Z9 InterPro 565
UniProtKB:A0AC58I500 InterPro 550
UniProtKB:A0AC58I501 InterPro 542
UniProtKB:A0AC58I503 InterPro 519
UniProtKB:A0AC58I504 InterPro 537
UniProtKB:A0AC58I505 InterPro 537
UniProtKB:A0AC58I506 InterPro 586
UniProtKB:A0AC58I507 InterPro 576
UniProtKB:A0AC58I508 InterPro 498
UniProtKB:A0AC58I509 InterPro 565
UniProtKB:A0AC58I510 InterPro 511
UniProtKB:A0AC58I511 InterPro 526
UniProtKB:A0AC58I512 InterPro 516
UniProtKB:A0AC58I514 InterPro 537
UniProtKB:A0AC58I515 InterPro 531
UniProtKB:A0AC58I516 InterPro 519
UniProtKB:A0AC58I517 InterPro 532
UniProtKB:A0AC58I518 InterPro 516
UniProtKB:A0AC58I519 InterPro 513
UniProtKB:A0AC58I520 InterPro 531
UniProtKB:A0AC58I521 InterPro 526
UniProtKB:A0AC58I524 InterPro 524
UniProtKB:A0AC58I527 InterPro 495
UniProtKB:A0AC58I532 InterPro 511
UniProtKB:A0AC58I536 InterPro 490
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dab1a-201 (1) Ensembl 1,632 nt
mRNA dab1a-202 (1) Ensembl 1,962 nt
mRNA dab1a-205 (1) Ensembl 2,535 nt
mRNA dab1a-206 (1) Ensembl 1,949 nt
mRNA dab1a-207 (1) Ensembl 1,714 nt
mRNA dab1a-208 (1) Ensembl 2,168 nt
ncRNA dab1a-002 (1) Ensembl 2,680 nt
ncRNA dab1a-004 (1) Ensembl 2,168 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations