ZFIN is now using GRCz12tu for Genomic Data
Gene

arhgef28a

ID
ZDB-GENE-060531-28
Name
Rho guanine nucleotide exchange factor (GEF) 28a
Symbol
arhgef28a Nomenclature History
Previous Names
  • arhgef28 (1)
  • rgnef (1)
  • p190RhoGEF (1)
  • si:ch211-1o14.5 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within Golgi organization; cell-matrix adhesion; and muscle tissue morphogenesis. Predicted to be located in cytoplasm. Is expressed in ball; head; notochord; somite; and trunk. Orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Cao et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef28a Human Ortholog
No data available
Associated With arhgef28a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR037819 ARHGEF28, PH domain
Domain IPR041020 ARHGEF1-like, PH domain
Family IPR051632 Rho guanine nucleotide exchange factor
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR046349 C1-like domain superfamily
Domain Details Per Protein
Protein Additional Resources Length ARHGEF1-like, PH domain ARHGEF28, PH domain C1-like domain superfamily Dbl homology (DH) domain superfamily Dbl homology domain PH-like domain superfamily Pleckstrin homology domain Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Rho guanine nucleotide exchange factor
UniProtKB:F6P6M2 InterPro 1753
UniProtKB:A0A8M9PYS9 InterPro 1782
UniProtKB:A0A8M9QEQ4 InterPro 1441
UniProtKB:A0A8M3ASG5 InterPro 1810
UniProtKB:A0A8M6YZA7 InterPro 1783
UniProtKB:A0A8M9Q483 InterPro 1816
UniProtKB:A0A8M6Z0T3 InterPro 1754
UniProtKB:A0A8M9PL62 InterPro 1787
UniProtKB:A0A8M6YYE7 InterPro 1817
UniProtKB:A0A8M9QEQ0 InterPro 1809
UniProtKB:A0A8M6Z734 InterPro 1442
UniProtKB:A0A8M6Z6H3 InterPro 1788
UniProtKB:A0AB32TEP9 InterPro 1781
UniProtKB:A0AB32TEQ4 InterPro 1747
UniProtKB:A0AB32TQ17 InterPro 1746
UniProtKB:A0AC58JPM1 InterPro 1405
UniProtKB:A0AC58JPM5 InterPro 1782
UniProtKB:A0AC58JPM9 InterPro 1775
UniProtKB:A0AC58JPN4 InterPro 1412
UniProtKB:A0AC58JPP0 InterPro 1400
UniProtKB:A0AC58JPP4 InterPro 1378
UniProtKB:A0AC58JPP8 InterPro 1407
UniProtKB:A0AC58JPQ3 InterPro 1371
UniProtKB:A0AC58JPQ9 InterPro 1441
UniProtKB:A0AC58JPR2 InterPro 1434
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arhgef28-202 (1)
Ensembl
Ensembl 6,200 nt
ZFIN BLAST
mRNA arhgef28a-201 (1)
Ensembl
Ensembl 6,091 nt
ZFIN BLAST
mRNA arhgef28a-203 (1)
Ensembl
Ensembl 4,803 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.