ZFIN is now using GRCz12tu for Genomic Data
Gene
wnt2bb
- ID
- ZDB-GENE-060824-6
- Name
- wingless-type MMTV integration site family, member 2Bb
- Symbol
- wnt2bb Nomenclature History
- Previous Names
-
- prometheus
- prt
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Involved in liver development. Acts upstream of or within several processes, including angiogenesis; hepaticobiliary system development; and swim bladder development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; heart; mesoderm; nervous system; and primordial vasculature. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human WNT2B (Wnt family member 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diarrhea 9 | 618168 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Wnt | Wnt-2 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:Q1L130 | InterPro | 396 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt2bb-201
(1)
|
Ensembl | 1,413 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers