Gene
zfx
- ID
- ZDB-GENE-061220-2
- Name
- zinc finger protein X-linked
- Symbol
- zfx Nomenclature History
- Previous Names
-
- wu:fb70f06
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in brain. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to several human genes including ZFX (zinc finger protein X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Shepherdson et al., 2024
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shepherdson et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, X-linked syndromic 37 | 301118 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Transcriptional activator, Zfx/Zfy domain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
| UniProtKB:E7F557 | InterPro | 739 |
Interactions and Pathways
No data available
Plasmids
No data available