ackr3a

ID

ZDB-GENE-070301-5

Name

atypical chemokine receptor 3a

Symbol

ackr3a Nomenclature History

Previous Names

cxcr7a (1)
drRDC1a (1)
si:dkey-191g15.12
si:dkeyp-74a11.11

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within chemotaxis and posterior lateral line neuromast primordium migration. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including midbrain hindbrain boundary neural rod; midbrain neural rod; midbrain neural tube; presumptive endoderm; and rhombomere. Orthologous to human ACKR3 (atypical chemokine receptor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Venkiteswaran et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ackr3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Oculomotor-abducens synkinesis	619215

Associated With ackr3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR001416	Atypical chemokine receptor 3
Family	IPR047143	G-protein coupled estrogen receptor 1-like
Family	IPR050119	C-C chemokine receptor type 1-9-like