ZFIN is now using GRCz12tu for Genomic Data
Gene
adgrb3
- ID
- ZDB-GENE-070424-99
- Name
- adhesion G protein-coupled receptor B3
- Symbol
- adgrb3 Nomenclature History
- Previous Names
-
- bai3
- zgc:163001
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and neuron remodeling. Predicted to act upstream of or within cell surface receptor signaling pathway and negative regulation of angiogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane; postsynapse; and synaptic cleft. Is expressed in brain; eye; and testis. Orthologous to human ADGRB3 (adhesion G protein-coupled receptor B3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR032471 | AGRL2-4 , GAIN subdomain A |
| Domain | IPR043838 | Adhesion G protein-coupled receptor B, N-terminal domain |
| Domain | IPR057244 | GAIN, subdomain B |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR008077 | GPCR, family 2, brain-specific angiogenesis inhibitor |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Adhesion G protein-coupled receptor B, N-terminal domain | AGRL2-4 , GAIN subdomain A | GAIN domain superfamily | GAIN, subdomain B | GPCR, family 2, brain-specific angiogenesis inhibitor | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPS motif | Thrombospondin type-1 (TSP1) repeat |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B381 | InterPro | 1493 | ||||||||||||
| UniProtKB:A0A8M9QG42 | InterPro | 1437 | ||||||||||||
| UniProtKB:A0A8M1RNS0 | InterPro | 1528 | ||||||||||||
| UniProtKB:A0A8M9Q536 | InterPro | 343 | ||||||||||||
| UniProtKB:A0AB32SZX2 | InterPro | 1525 | ||||||||||||
| UniProtKB:A0AB32SZZ1 | InterPro | 1560 | ||||||||||||
| UniProtKB:A0AB32T2V0 | InterPro | 1523 | ||||||||||||
| UniProtKB:A0AB32T5S7 | InterPro | 1469 | ||||||||||||
| UniProtKB:A0AC58H2W0 | InterPro | 1527 | ||||||||||||
| UniProtKB:A0AC58H2W1 | InterPro | 1493 | ||||||||||||
| UniProtKB:A0AC58H2W2 | InterPro | 1492 | ||||||||||||
| UniProtKB:A0AC58H2W6 | InterPro | 1490 | ||||||||||||
| UniProtKB:A0AC58H2W8 | InterPro | 1488 | ||||||||||||
| UniProtKB:A0AC58H2X2 | InterPro | 1495 | ||||||||||||
| UniProtKB:A0AC58H2X4 | InterPro | 1491 | ||||||||||||
| UniProtKB:A0AC58H2X9 | InterPro | 1460 | ||||||||||||
| UniProtKB:A0AC58H2Y1 | InterPro | 1423 | ||||||||||||
| UniProtKB:A0AC58H2Y2 | InterPro | 1437 | ||||||||||||
| UniProtKB:A0AC58H2Y5 | InterPro | 1456 | ||||||||||||
| UniProtKB:A0AC58H2Y6 | InterPro | 1434 | ||||||||||||
| UniProtKB:A0AC58H2Y9 | InterPro | 1402 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgrb3-201
(1)
|
Ensembl | 2,310 nt | ||
| mRNA |
adgrb3-202
(1)
|
Ensembl | 3,647 nt | ||
| mRNA |
adgrb3-203
(1)
|
Ensembl | 1,981 nt | ||
| mRNA |
adgrb3-204
(1)
|
Ensembl | 789 nt | ||
| mRNA |
adgrb3-205
(1)
|
Ensembl | 807 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers