ZFIN is now using GRCz12tu for Genomic Data
Gene
vps13c
- ID
- ZDB-GENE-070426-4
- Name
- vacuolar protein sorting 13 homolog C
- Symbol
- vps13c Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable phospholipid transfer activity. Predicted to be involved in intermembrane lipid transfer; macroautophagy; and mitochondrion organization. Predicted to act upstream of or within lipid transport. Predicted to be active in endosome membrane and mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Parkinson's disease 23. Orthologous to human VPS13C (vacuolar protein sorting 13 homolog C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from O'Hare et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinson's disease 23 | Alliance | Parkinson disease 23, autosomal recessive, early onset | 616840 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR009543 | Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain |
| Domain | IPR026854 | Vacuolar protein sorting-associated protein 13, N-terminal domain |
| Domain | IPR056747 | VPS13-like, middle region |
| Domain | IPR056748 | Intermembrane lipid transfer protein VPS13-like, C-terminal |
| Family | IPR026847 | Vacuolar protein sorting-associated protein 13 |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
vps13c-201
(1)
|
Ensembl | 13,930 nt | ||
| ncRNA |
vps13c-003
(1)
|
Ensembl | 641 nt | ||
| ncRNA |
vps13c-005
(1)
|
Ensembl | 844 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance