ZFIN is now using GRCz12tu for Genomic Data
Gene

mmp25a

ID
ZDB-GENE-070820-22
Name
matrix metallopeptidase 25a
Symbol
mmp25a Nomenclature History
Previous Names
  • mmp25
  • MMPLa (1)
  • si:ch73-248e21.6
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular matrix and membrane. Predicted to be active in extracellular space. Orthologous to human MMP25 (matrix metallopeptidase 25).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Crawford et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mmp25a Human Ortholog
No data available
Associated With mmp25a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000585 Hemopexin-like domain
Domain IPR001818 Peptidase M10, metallopeptidase
Domain IPR002477 Peptidoglycan binding-like
Domain IPR006026 Peptidase, metallopeptidase
Domain IPR008015 GMP phosphodiesterase, delta subunit
Domain IPR033739 Peptidase M10A, catalytic domain
Family IPR021190 Peptidase M10A
Family IPR051519 PDE6D/unc-119 myristoyl-binding
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036365 PGBD-like superfamily
Homologous_superfamily IPR036375 Hemopexin-like domain superfamily
Homologous_superfamily IPR037036 GMP phosphodiesterase, delta subunit superfamily
Repeat IPR018487 Hemopexin-like repeats
Domain Details Per Protein
Protein Additional Resources Length GMP phosphodiesterase, delta subunit GMP phosphodiesterase, delta subunit superfamily Hemopexin-like domain Hemopexin-like domain superfamily Hemopexin-like repeats Immunoglobulin E-set Metallopeptidase, catalytic domain superfamily PDE6D/unc-119 myristoyl-binding Peptidase M10A Peptidase M10A, catalytic domain Peptidase M10, metallopeptidase Peptidase, metallopeptidase Peptidoglycan binding-like PGBD-like superfamily
UniProtKB:A0A8M9PJH5 InterPro 514
UniProtKB:A0A8M9PYF1 InterPro 514
UniProtKB:A0A8M9PFG4 InterPro 488
UniProtKB:A0A8M9PQG7 InterPro 488
UniProtKB:A0A8M3AR02 InterPro 261
UniProtKB:A0AC58J2H3 InterPro 492
UniProtKB:A0AC58J2H6 InterPro 550
UniProtKB:A0AC58J2H8 InterPro 542
UniProtKB:A0AC58J2I2 InterPro 261
UniProtKB:A0AC58J2I4 InterPro 518
UniProtKB:A0AC58J2K0 InterPro 568
UniProtKB:A0AB32TLQ2 InterPro 526
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mmp25a-201 (1) Ensembl 1,737 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations