spint1b

ID

ZDB-GENE-071218-1

Name

serine peptidase inhibitor, Kunitz type 1 b

Symbol

spint1b Nomenclature History

Previous Names

hai1b (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within epidermis development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in gut; lateral line primordium; and primitive olfactory epithelium. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Carney et al., 2007

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With spint1b Human Ortholog

No data available

Associated With spint1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020901	Proteinase inhibitor I2, Kunitz, conserved site
Conserved_site	IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site
Domain	IPR002223	Pancreatic trypsin inhibitor Kunitz domain
Domain	IPR011106	Seven cysteines, N-terminal
Domain	IPR013980	MANSC domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR035986	PKD domain superfamily
Homologous_superfamily	IPR036055	LDL receptor-like superfamily
Homologous_superfamily	IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily
Repeat	IPR002172	Low-density lipoprotein (LDL) receptor class A repeat