smarcc1a

ID

ZDB-GENE-080514-3

Name

SWI/SNF related BAF chromatin remodeling complex subunit C1a

Symbol

smarcc1a Nomenclature History

Previous Names

smarcc1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable histone binding activity. Acts upstream of or within cardiac chamber morphogenesis and definitive hemopoiesis. Located in cytoplasm and nucleus. Is expressed in head; tail bud; and telencephalon. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human SMARCC1 (SWI/SNF related BAF chromatin remodeling complex subunit C1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 12 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smarcc1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Hydrocephalus, congenital, 5, susceptibility to}	620241

Associated With smarcc1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR007526	SWIRM domain
Domain	IPR017884	SANT domain
Domain	IPR032448	SMARCC, SWIRM-associated domain
Domain	IPR032450	SMARCC, N-terminal
Domain	IPR032451	SMARCC, C-terminal
Domain	IPR049898	MarR-like, BRCT and chromo domains module
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036420	BRCT domain superfamily