Gene
adrb3b
- ID
- ZDB-GENE-081022-154
- Name
- adrenoceptor beta 3b
- Symbol
- adrb3b Nomenclature History
- Previous Names
-
- zgc:194843
- zgc:194852
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable beta3-adrenergic receptor activity and epinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure; and positive regulation of MAPK cascade. Predicted to be active in plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; metabolic dysfunction-associated steatotic liver disease; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wang et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
| UniProtKB:B3DIE4 | InterPro | 405 | ||
| UniProtKB:A0A8M9QKR9 | InterPro | 417 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb3b-201
(1)
|
Ensembl | 1,676 nt |
Interactions and Pathways
No data available
Plasmids
No data available