adcy5

ID

ZDB-GENE-081104-470

Name

adenylate cyclase 5

Symbol

adcy5 Nomenclature History

Previous Names

ac5 (1)
fan (1)
fantasma (1)
si:dkey-178j17.2
si:dkeyp-60a7.2

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable adenylate cyclase activity. Acts upstream of or within melanosome localization; regulation of protein phosphorylation; and response to ethanol. Predicted to be located in cilium and membrane. Predicted to be active in plasma membrane. Is expressed in brain; head; and heart. Orthologous to human ADCY5 (adenylate cyclase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adcy5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Dyskinesia with orofacial involvement, autosomal dominant	606703
		Dyskinesia with orofacial involvement, autosomal recessive	619647
		Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	619651

Associated With adcy5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase
Domain	IPR009398	Adenylate cyclase, conserved domain
Domain	IPR032628	Adenylate cyclase, N-terminal
Family	IPR030672	Adenylate cyclase
Homologous_superfamily	IPR029787	Nucleotide cyclase