Gene
rhobtb2a
- ID
- ZDB-GENE-081105-67
- Name
- Rho related BTB domain containing 2a
- Symbol
- rhobtb2a Nomenclature History
- Previous Names
-
- si:dkey-263f15.2
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Cdc42 protein signal transduction; actin filament organization; and endocytosis. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 64. Orthologous to human RHOBTB2 (Rho related BTB domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Salas-Vidal et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 64 | Alliance | Developmental and epileptic encephalopathy 64 | 618004 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0AB32TW99 | InterPro | 575 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rhobtb2a-201
(1)
|
Ensembl | 396 nt | ||
| mRNA |
rhobtb2a-202
(1)
|
Ensembl | 1,411 nt |
Interactions and Pathways
No data available
Plasmids
No data available