ZFIN is now using GRCz12tu for Genomic Data
Gene
spock2
- ID
- ZDB-GENE-090312-170
- Name
- SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
- Symbol
- spock2 Nomenclature History
- Previous Names
-
- im:7149140
- si:dkeyp-115d2.5
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity and metalloendopeptidase inhibitor activity. Predicted to be involved in regulation of cell-substrate adhesion. Predicted to be active in extracellular matrix. Is expressed in brain and peripheral olfactory organ. Orthologous to human SPOCK2 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149140 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000716 | Thyroglobulin type-1 |
| Domain | IPR002350 | Kazal domain |
| Domain | IPR019577 | SPARC/Testican, calcium-binding domain |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
| Homologous_superfamily | IPR036857 | Thyroglobulin type-1 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-hand domain pair | Kazal domain | Kazal domain superfamily | SPARC/Testican, calcium-binding domain | Thyroglobulin type-1 | Thyroglobulin type-1 superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8Q8S3 | InterPro | 419 | ||||||
| UniProtKB:A0A8M1RM78 | InterPro | 422 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spock2-201
(1)
|
Ensembl | 1,338 nt | ||
| mRNA |
spock2-202
(1)
|
Ensembl | 1,704 nt | ||
| mRNA |
spock2-203
(1)
|
Ensembl | 276 nt | ||
| mRNA |
spock2-204
(1)
|
Ensembl | 2,282 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers