ZFIN is now using GRCz12tu for Genomic Data
Gene

ubr4

ID
ZDB-GENE-090313-341
Name
ubiquitin protein ligase E3 component n-recognin 4
Symbol
ubr4 Nomenclature History
Previous Names
  • si:dkey-7c22.2
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in cytoplasm protein quality control and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to be active in cytoplasm. Orthologous to human UBR4 (ubiquitin protein ligase E3 component n-recognin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tilghman et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ubr4 Human Ortholog
No data available
Associated With ubr4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003126 Zinc finger, UBR-type
Domain IPR025704 E3 ubiquitin ligase UBR4, C-terminal
Domain IPR045841 E3 ubiquitin-protein ligase UBR4, N-terminal
Domain IPR047509 E3 ubiquitin-protein ligase UBR4-like, UBR-box
Domain IPR056530 E3 ubiquitin-protein ligase UBR4-like domain
Family IPR045189 E3 ubiquitin ligase UBR4-like
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Armadillo-type fold E3 ubiquitin ligase UBR4, C-terminal E3 ubiquitin ligase UBR4-like E3 ubiquitin-protein ligase UBR4-like domain E3 ubiquitin-protein ligase UBR4-like, UBR-box E3 ubiquitin-protein ligase UBR4, N-terminal WD40-repeat-containing domain superfamily Zinc finger, UBR-type
UniProtKB:A0A8M6Z3V7 InterPro 5190
UniProtKB:A0A8M6YVC3 InterPro 5192
UniProtKB:A0A8M9PWV7 InterPro 5184
UniProtKB:A0A8M9PWV4 InterPro 5192
UniProtKB:A0A8M6YVZ4 InterPro 5187
UniProtKB:A0A8M9PQN9 InterPro 5144
UniProtKB:A0A8M9Q7V9 InterPro 5192
UniProtKB:A0A8M3AVE1 InterPro 5161
UniProtKB:A0A8M9PDY5 InterPro 5197
UniProtKB:A0A8M6YXU8 InterPro 5196
UniProtKB:A0A8M6Z3V2 InterPro 5197
UniProtKB:A0A8M6YVC7 InterPro 5181
UniProtKB:A0A8M6YVB9 InterPro 5198
UniProtKB:A0A8M6Z4I7 InterPro 5183
UniProtKB:A0AB32TNY6 InterPro 5178
UniProtKB:A0AC58IL31 InterPro 5218
UniProtKB:A0AC58IL34 InterPro 5213
UniProtKB:A0AC58IL35 InterPro 5219
UniProtKB:A0AC58IL36 InterPro 5234
UniProtKB:A0AC58IL39 InterPro 5223
UniProtKB:A0AC58IL40 InterPro 5225
UniProtKB:A0AC58IL41 InterPro 5233
UniProtKB:A0AC58IL43 InterPro 5190
UniProtKB:A0AC58IL44 InterPro 5191
UniProtKB:A0AC58IL46 InterPro 5239
UniProtKB:A0AC58IL49 InterPro 5167
UniProtKB:A0AC58IL50 InterPro 5169
UniProtKB:A0AC58IL51 InterPro 5166
UniProtKB:A0AC58IL52 InterPro 5176
UniProtKB:A0AC58IL53 InterPro 5169
UniProtKB:A0AC58IL55 InterPro 5175
UniProtKB:A0AC58IL57 InterPro 5176
UniProtKB:A0AC58IL58 InterPro 5174
UniProtKB:A0AC58IL59 InterPro 5164
UniProtKB:A0AC58IL61 InterPro 5165
UniProtKB:A0AC58IL62 InterPro 5238
UniProtKB:A0AC58IL63 InterPro 5181
UniProtKB:A0AC58IL64 InterPro 5189
UniProtKB:A0AC58IL65 InterPro 5150
UniProtKB:A0AC58IL66 InterPro 5234
UniProtKB:A0AC58IL67 InterPro 5152
UniProtKB:A0AC58IL68 InterPro 5158
UniProtKB:A0AC58IL69 InterPro 5146
UniProtKB:A0AC58IL70 InterPro 5154
UniProtKB:A0AC58IL71 InterPro 5156
UniProtKB:A0AC58IL72 InterPro 5155
UniProtKB:A0AC58IL74 InterPro 5143
UniProtKB:A0AC58IL75 InterPro 5157
UniProtKB:A0AC58IL76 InterPro 5145
UniProtKB:A0AC58IL77 InterPro 5180
UniProtKB:A0AC58IL78 InterPro 5159
UniProtKB:A0AC58IL79 InterPro 5240
UniProtKB:A0AC58IL80 InterPro 5163
UniProtKB:A0AC58IL83 InterPro 5177
UniProtKB:A0AC58IL90 InterPro 5158
UniProtKB:A0AC58IL97 InterPro 5138
UniProtKB:A0AC58ILA0 InterPro 5184
UniProtKB:A0AC58ILA1 InterPro 5143
UniProtKB:A0AC58ILA5 InterPro 5137
UniProtKB:A0AC58ILB6 InterPro 5160
UniProtKB:A0AC58ILD5 InterPro 5140
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ubr4-201 (1) Ensembl 15,869 nt
mRNA ubr4-204 (1) Ensembl 15,519 nt
ncRNA ubr4-002 (1) Ensembl 939 nt
ncRNA ubr4-003 (1) Ensembl 766 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations