ZFIN is now using GRCz12tu for Genomic Data
Gene
gnb4a
- ID
- ZDB-GENE-091102-1
- Name
- guanine nucleotide binding protein (G protein), beta polypeptide 4a
- Symbol
- gnb4a Nomenclature History
- Previous Names
-
- gnb4
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable signaling receptor complex adaptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in head; neuromast; and posterior lateral line primordium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate F. Orthologous to human GNB4 (G protein subunit beta 4).
- Genome Resources
-
- Alliance (1)
- Gene:100332205 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xu et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease dominant intermediate F | Alliance | Charcot-Marie-Tooth disease, dominant intermediate F | 615185 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9NZA4 | InterPro | 340 |
| UniProtKB:A0AC58H9V3 | InterPro | 340 |
| UniProtKB:A0AC58H9X5 | InterPro | 340 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance