ZFIN is now using GRCz12tu for Genomic Data
Gene
wwc1
- ID
- ZDB-GENE-091118-8
- Name
- WW and C2 domain containing 1
- Symbol
- wwc1 Nomenclature History
- Previous Names
-
- si:dkey-174n5.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable kinase binding activity and molecular adaptor activity. Predicted to be involved in several processes, including negative regulation of organ growth; regulation of DNA-templated transcription; and regulation of hippo signaling. Predicted to be active in cytoplasm. Orthologous to human WWC1 (WW and C2 domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Fitzgerald et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Memory, enhanced, QTL] | 615602 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR001202 | WW domain |
| Domain | IPR037771 | WWC, C2 domain |
| Domain | IPR057747 | WWC1-like, helical hairpin |
| Family | IPR051105 | WWC/KIBRA Hippo Pathway Regulators |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036020 | WW domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | WWC1-like, helical hairpin | WWC, C2 domain | WWC/KIBRA Hippo Pathway Regulators | WW domain | WW domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E9QGC4 | InterPro | 1112 | |||||||
| UniProtKB:A0ACD6B5Z6 | InterPro | 1112 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers