ZFIN is now using GRCz12tu for Genomic Data
Gene
usp18
- ID
- ZDB-GENE-100210-2
- Name
- ubiquitin specific peptidase 18
- Symbol
- usp18 Nomenclature History
- Previous Names
-
- si:ch73-352p4.3
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables ubiquitin-like protein binding activity. Acts upstream of or within cranial skeletal system development. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including USP18 (ubiquitin specific peptidase 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Pseudo-TORCH syndrome 2 | 617397 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Ubiquitin carboxyl-terminal hydrolases | Ubiquitin specific protease, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:E7EYZ1 | InterPro | 337 |
Interactions and Pathways
No data available
Plasmids
No data available