axl

ID

ZDB-GENE-100812-8

Name

AXL receptor tyrosine kinase

Symbol

axl Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in several processes, including natural killer cell differentiation; platelet activation; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Challa et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With axl Human Ortholog

No data available

Associated With axl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M6Z1G5	InterPro	919
UniProtKB:A0AC58HEC8	InterPro	920
UniProtKB:A0AC58HED1	InterPro	920
UniProtKB:A0AC58HED2	InterPro	919
UniProtKB:A0AC58HEE1	InterPro	873
UniProtKB:A0AC58HEE4	InterPro	919
UniProtKB:A0AC58HEG3	InterPro	874
UniProtKB:A0AC58HEH4	InterPro	920
UniProtKB:A0AC58HEI2	InterPro	919