ZFIN is now using GRCz12tu for Genomic Data
Gene
cxcl8b.1
- ID
- ZDB-GENE-101026-3
- Name
- chemokine (C-X-C motif) ligand 8b, duplicate 1
- Symbol
- cxcl8b.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Acts upstream of or within several processes, including leukocyte migration involved in inflammatory response; neutrophil chemotaxis; and response to bacterium. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain and intestine. Human ortholog(s) of this gene implicated in several diseases, including acute pyelonephritis; autoimmune uveitis; gastritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human CXCL8 (C-X-C motif chemokine ligand 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zuñiga-Traslaviña et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily | CXC Chemokine domain |
|---|---|---|---|---|---|---|
| UniProtKB:N0GW19 | InterPro | 118 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cxcl8b.1-201
(1)
|
Ensembl | 714 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers