ZFIN is now using GRCz12tu for Genomic Data
Gene
kcnj5
- ID
- ZDB-GENE-120215-97
- Name
- potassium inwardly rectifying channel subfamily J member 5
- Symbol
- kcnj5 Nomenclature History
- Previous Names
-
- si:ch73-13p12.1
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in brain; heart; myotome; pectoral fin; and pharyngeal arch. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| long QT syndrome 13 | Alliance | Long QT syndrome 13 | 613485 |
| primary hyperaldosteronism | Alliance | Hyperaldosteronism, familial, type III | 613677 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR040445 | Potassium channel, inwardly rectifying, transmembrane domain |
| Domain | IPR041647 | Inward rectifier potassium channel, C-terminal |
| Family | IPR016449 | Potassium channel, inwardly rectifying, Kir |
| Homologous_superfamily | IPR013518 | Potassium channel, inwardly rectifying, Kir, cytoplasmic |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin E-set | Inward rectifier potassium channel, C-terminal | Potassium channel, inwardly rectifying, Kir | Potassium channel, inwardly rectifying, Kir, cytoplasmic | Potassium channel, inwardly rectifying, transmembrane domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAD0 | InterPro | 425 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers