ZFIN is now using GRCz12tu for Genomic Data
Gene
tmc5
- ID
- ZDB-GENE-120411-6
- Name
- transmembrane channel like 5
- Symbol
- tmc5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mechanosensitive monoatomic ion channel activity. Acts upstream of or within cilium movement. Located in cytoplasm. Is expressed in neuromast and otic vesicle. Orthologous to human TMC5 (transmembrane channel like 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Geng et al., 2026
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TMC domain | Transmembrane channel-like protein |
|---|---|---|---|---|
| UniProtKB:A0A8M3B8A3 | InterPro | 487 | ||
| UniProtKB:E7FDU7 | InterPro | 685 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmc5-201
(1)
|
Ensembl | 2,720 nt | ||
| ncRNA |
si:dkey-202l16.5-002
(1)
|
Ensembl | 628 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance