Gene
vegfba
- ID
- ZDB-GENE-120510-3
- Name
- vascular endothelial growth factor Ba
- Symbol
- vegfba Nomenclature History
- Previous Names
-
- si:ch211-245d7.5
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Acts upstream of or within cerebellum vasculature development and neuron development. Predicted to be active in extracellular space. Is expressed in brain; head; mid cerebral vein; somite; and trunk. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Orthologous to human VEGFB (vascular endothelial growth factor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Jensen et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023581 | Platelet-derived growth factor, conserved site |
| Domain | IPR000072 | PDGF/VEGF domain |
| Family | IPR050507 | Platelet-derived/Vascular endothelial growth factor |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
| Homologous_superfamily | IPR036841 | Vascular endothelial growth factor, heparin-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived/Vascular endothelial growth factor | Vascular endothelial growth factor, heparin-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZR4 | InterPro | 246 | |||||
| UniProtKB:A0A8M2B3Z6 | InterPro | 246 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
vegfba-201
(1)
|
Ensembl | 7,435 nt | ||
| ncRNA |
vegfba-002
(1)
|
Ensembl | 671 nt |
Interactions and Pathways
No data available
Plasmids
No data available