adamts17

ID

ZDB-GENE-121030-7

Name

ADAM metallopeptidase with thrombospondin type 1 motif, 17

Symbol

adamts17 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization and proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and thymus. Human ortholog(s) of this gene implicated in Weill-Marchesani syndrome. Orthologous to human ADAMTS17 (ADAM metallopeptidase with thrombospondin type 1 motif 17).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Brunet et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adamts17 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Weill-Marchesani syndrome 4	Alliance	Weill-Marchesani 4 syndrome, recessive	613195

Associated With adamts17 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9QHG7	InterPro	1134
UniProtKB:A0AC58G343	InterPro	1134
UniProtKB:A0AC58G347	InterPro	1109
UniProtKB:A0AC58G361	InterPro	812
UniProtKB:A0AC58G364	InterPro	787