Gene
trim8a
- ID
- ZDB-GENE-130107-1
- Name
- tripartite motif containing 8a
- Symbol
- trim8a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Predicted to be involved in innate immune response and suppression of viral release by host. Located in nucleus. Is expressed in central nervous system; midbrain; and retina. Orthologous to human TRIM8 (tripartite motif containing 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Micale et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Focal segmental glomerulosclerosis and neurodevelopmental syndrome | 619428 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase TRIM/RNF | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:E7FCI6 | InterPro | 567 | ||||
| UniProtKB:J9UF94 | InterPro | 560 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trim8a-201
(1)
|
Ensembl | 4,253 nt | ||
| mRNA |
trim8a-202
(1)
|
Ensembl | 1,683 nt |
Interactions and Pathways
No data available
Plasmids
No data available