ZFIN is now using GRCz12tu for Genomic Data
Gene
clpxb
- ID
- ZDB-GENE-130404-1
- Name
- caseinolytic mitochondrial matrix peptidase chaperone subunit Xb
- Symbol
- clpxb Nomenclature History
- Previous Names
-
- fc31b05
- fj85g10
- wu:fc31b05
- wu:fj85g10
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Rondelli et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Protoporphyria, erythropoietic, 2 | 618015 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR019489 | Clp ATPase, C-terminal |
| Domain | IPR059067 | ATP-dependent ClpX-like chaperone, zinc ribbon domain |
| Domain | IPR059188 | ClpX-like, zinc ribbon domain |
| Family | IPR004487 | Clp protease, ATP-binding subunit ClpX |
| Family | IPR050052 | ATP-dependent Clp protease ATP-binding subunit ClpX |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ATPase, AAA-type, core | ATP-dependent Clp protease ATP-binding subunit ClpX | ATP-dependent ClpX-like chaperone, zinc ribbon domain | Clp ATPase, C-terminal | Clp protease, ATP-binding subunit ClpX | ClpX-like, zinc ribbon domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F9J1 | InterPro | 618 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers