piezo2a

ID

ZDB-GENE-131119-76

Name

piezo-type mechanosensitive ion channel component 2a

Symbol

piezo2a Nomenclature History

Previous Names

piezo1b (1)
piezo2a.1
piezo2a.2
piezo2a
si:ch1073-433p8.1 (1)
zmp:0000000946 (1)
zmp:0000001249

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable mechanosensitive monoatomic cation channel activity. Acts upstream of or within vascular associated smooth muscle cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in bulbus arteriosus and vertebral column.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With piezo2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
distal arthrogryposis type 3	Alliance	Arthrogryposis, distal, type 3	114300
distal arthrogryposis type 5	Alliance	Arthrogryposis, distal, type 5	108145
		Arthrogryposis, distal, with impaired proprioception and touch	617146
		?Marden-Walker syndrome	248700

Associated With piezo2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PXR1	InterPro	2752
UniProtKB:A0AC58IT82	InterPro	2753
UniProtKB:A0AC58IT89	InterPro	2753
UniProtKB:A0AC58ITA0	InterPro	2752
UniProtKB:A0AC58ITA3	InterPro	2752
UniProtKB:A0AC58ITC1	InterPro	2622
UniProtKB:A0AC58ITC2	InterPro	2623