smarca4b

ID

ZDB-GENE-140106-1

Name

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4b

Symbol

smarca4b Nomenclature History

Previous Names

zmp:0000001041 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA binding activity; chromatin binding activity; and nucleosome array spacer activity. Predicted to be involved in heterochromatin formation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in chromatin and nucleus. Is expressed in telencephalon.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smarca4b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 4	Alliance	Coffin-Siris syndrome 4	614609
rhabdoid tumor predisposition syndrome 2	Alliance	{Rhabdoid tumor predisposition syndrome 2}	613325
		?Otosclerosis 12	620792

Associated With smarca4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9QFL5	InterPro	1619
UniProtKB:A0AC58JSR5	InterPro	1621
UniProtKB:A0AC58JSS1	InterPro	523
UniProtKB:A0AC58JSS8	InterPro	1099
UniProtKB:A0AC58JST0	InterPro	1607
UniProtKB:A0AC58JSU1	InterPro	1620
UniProtKB:A0AC58JSV4	InterPro	1608