ZFIN is now using GRCz12tu for Genomic Data
Gene
c3a.4
- ID
- ZDB-GENE-140822-3
- Name
- complement C3a, tandem duplicate 4
- Symbol
- c3a.4 Nomenclature History
- Previous Names
-
- c3.4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz11
- Annotation Status
- Not in current annotation release
- Description
- Predicted to be located in extracellular region. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Forn-Cuní et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| age related macular degeneration 9 | Alliance | {Macular degeneration, age-related, 9} | 611378 |
| complement component 3 deficiency | Alliance | C3 deficiency | 613779 |
| {Hemolytic uremic syndrome, atypical, susceptibility to, 5} | 612925 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:F1QYN0 | InterPro | 1606 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- No data available