ZFIN is now using GRCz12tu for Genomic Data
Gene
sprtn
- ID
- ZDB-GENE-170317-1
- Name
- SprT-like N-terminal domain
- Symbol
- sprtn Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable double-stranded DNA binding activity; metalloendopeptidase activity; and single-stranded DNA binding activity. Acts upstream of or within DNA damage response. Predicted to be located in chromatin and nucleus. Human ortholog(s) of this gene implicated in Ruijs-Aalfs syndrome. Orthologous to human SPRTN (SprT-like N-terminal domain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ruijs-Aalfs syndrome | Alliance | Ruijs-Aalfs syndrome | 616200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Rad18, zinc finger UBZ4-type | Spartan-like, zinc binding domain | SprT-like | SprT-like domain-containing protein Spartan |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0G2L7I0 | InterPro | |||||
| UniProtKB:A0AB13A9G6 | InterPro | 636 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers