ZFIN is now using GRCz12tu for Genomic Data
Gene
pou3f3b
- ID
- ZDB-GENE-980526-140
- Name
- POU class 3 homeobox 3b
- Symbol
- pou3f3b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including head; nervous system; otic vesicle; pronephric duct; and spinal cord neural tube. Orthologous to human POU3F3 (POU class 3 homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Barske et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Snijders Blok-Fisher syndrome | 618604 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR016362 | POU-domain transcription factor, class 3 |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-domain transcription factor, class 3 | POU-specific domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:P79745 | InterPro | 443 | ||||||||
| UniProtKB:A0A8M2BFZ4 | InterPro | 440 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou3f3b-201
(1)
|
Ensembl | 3,403 nt | ||
| mRNA |
pou3f3b-202
(1)
|
Ensembl | 3,093 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers