ZFIN is now using GRCz12tu for Genomic Data
Gene
hhex
- ID
- ZDB-GENE-980526-299
- Name
- hematopoietically expressed homeobox
- Symbol
- hhex Nomenclature History
- Previous Names
-
- hex
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hemangioblast cell differentiation; liver morphogenesis; and regionalization. Acts upstream of or within with a positive effect on hepaticobiliary system development. Acts upstream of or within several processes, including circulatory system development; exocrine pancreas development; and positive regulation of endothelial cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; endocrine system; hepatoblast; and mesoderm. Orthologous to human HHEX (hematopoietically expressed homeobox).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 123 figures from 77 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 24 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox DNA-binding | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0G2KXR6 | InterPro | ||||||
| UniProtKB:Q9IAV3 | InterPro | 228 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers