ZFIN is now using GRCz12tu for Genomic Data
Gene
etv4
- ID
- ZDB-GENE-990415-71
- Name
- ETS variant transcription factor 4
- Symbol
- etv4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables sequence-specific DNA binding activity. Involved in positive regulation of DNA-templated transcription. Acts upstream of or within limb morphogenesis and pronephric nephron tubule epithelial cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including fin; head; mesoderm; nervous system; and neural keel. Orthologous to human ETV4 (ETS variant transcription factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 114 figures from 82 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76984 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Marra et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000418 | Ets domain |
| Domain | IPR006715 | PEA3-type ETS-domain transcription factor, N-terminal |
| Family | IPR046328 | ETS family |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ets domain | ETS family | PEA3-type ETS-domain transcription factor, N-terminal | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AY95 | InterPro | 495 | |||||
| UniProtKB:A0A8N1TV56 | InterPro | 494 | |||||
| UniProtKB:Q9PUQ1 | InterPro | 494 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers