Fig. 3
            
        
    
    
        
        
        
            Patterning of the Branchial Arches in a 5-Mo-Old dre Mutant 
 (A and B) The strict organization of the brachial arch into primary (p) and secondary (s) lamellae in a wild-type situation (100× magnification). Higher magnification shows stacks of single chondrocytes in the primary lamellae. 
 (C and D) Sectioning of a dre mutant shows disturbed patterning, resulting in the absence of secondary lamellae and the presence of foci of chondrocyte-like cells in the primary lamellae (arrowsHE, hematoxylin and eosin stain; wt, wild-type. 
 (E and F) Alcian Blue staining reveals the presence of differentiated chondrocytes in the wild-type (wt) primary lamellae, but not in the dre mutant, indicating that the differentiation of these chondrocytes is affected (200×). 
 (G and H) Branchial arches of uki and lep mutants appear to be wild-type (wt).
        
    
                
                    
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