Fig. 1
Conditioned Place Preference (CPP) test for morphine in adult zebrafish.
(A) Baseline preference of fish between dotted vs. white compartment as shown by percentage of initial time spend in compartment (n?=?23). (B) Preference behavior responses in the CPP tanks for control group as shown by percentage of time spent in conditioning compartment before (white bar) and after (grey bar) conditioning. (n?=?15). (C) Place preference behavior of adult zebrafish treated different morphine concentration (Control, n?=?15; 0.5 mg/L, n?=?18; 1.5 mg/L, n?=?16; 3 mg/L, n?=?15). Mean values were subjected to one way ANOVA and where applicable, ranked by Tukey test (P<0.05); mean percentage values with same letter are not significantly different.