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Publication: Brunal et al., 2021 - Effects of Constitutive and Acute Connexin 36 Deficiency on Brain-Wide Susceptibility to PTZ-Induced Neuronal Hyperactivity
All Figures: Figures for Brunal et al., 2021

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Figure 2

Activated caspase 3 positive cells by major brain division, comparing cx35.5-/- vs. wild type with and without PTZ. Representative sum stack projections of wild-type and cx35.5-/- larvae treated with media (A, B) or PTZ (D, E) and stained with anti-activated caspase-3. (C–F) Graphs depicting the number of activated caspase-3 positive cells in the rhombencephalon, mesencephalon, telencephalon, and diencephalon in wild-type (black) vs. cx35.5-/- (red) fish with treatment with (C) embryo medium (vehicle) or (F) PTZ. Data were analyzed using an unpaired t-test with Holm-Sidak's correction for multiple comparisons. Embryo medium (vehicle) treatment, wild type n = 5, cx35.5-/- n = 10. PTZ treatment, wild type n = 6, cx35.5-/- n = 8.

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