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Figure 5
Hyperglycemia is induced without loss of β cells in HFD, Li-PIC3, and Li-PIC3+HFD larvae. (A) Blood glucose levels for Tg(fabp10:cre), HFD, Li-PIC3, and Li-PIC3+HFD larvae. (B) β cell count in Tg(fabp10:cre), HFD, Li-PIC3, and Li-PIC3+HFD larvae. (C) Transcript levels for insulin Tg(fabp10:cre), HFD, Li-PIC3, and Li-PIC3+HFD larvae. (D) Levels of pck1, a marker of gluconeogenesis, in Tg(fabp10:cre), HFD, Li-PIC3, and Li-PIC3+HFD larvae. Statistical analysis was by one-way ANOVA, n = 3–9; * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
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