ZFIN Image: Liu et al., 2023, Figure 5.

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Figure Caption

Figure 5.

Changes in the morphology of craniofacial anomalies in teratogen-treated sox10:EGFP embryos. (A–F) Lateral live view of the first pharyngal arch (PA1) at 24 hpf. (A′–F′) Enlarged view of the white rectangle in panel A–F. Abnormal morphology of the PA1 was observed in the teratogen-treated embryos. (G–L) The developing palates (white arrowheads) and mandibles (yellow arrowheads) were disrupted in the teratogen-treated embryos at 48 hpf. (M–R) The PA1 defects resulted in a small-sized palate with clefting (cleft palate) and shortening in the Meckel’s cartilage at 72 hpf. e: eye. Scale bar: 100 µm.

Acknowledgments

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