Loss of Stc1a results in abnormal calcium deposits in a Trpv6-depndent manner. (A) Larvae (3 dpf) of the indicated genotypes treated with or without 10 μg/L CdCl2 for 2 days. They were subjected to Alizarin red staining at 5 dpf. Representative images are shown. Note the ectopic calcified structures in the yolk sac region (arrow) and kidney stones (arrow heads) in the mutant fish. Scale bar = 0.5 mm. (B) Alizarin red staining analysis of 7 dpf zebrafish larvae of the indicated genotypes. Representative images are shown. Note the ectopic calcified structures in the yolk sac region (arrow) and kidney stones (arrow heads) in the mutant fish. Scale bar = 0.2 mm.
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Full text @ Front Endocrinol (Lausanne)
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