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Fig. 6 Rescue of zebrafish morphant cardiac phenotypes by FLT4 variants. (A) Frontal views of 48 hpf embryos with myl7 expression staining (purple) used to label the heart. (B) Box and whisker plot showing the area of embryonic hearts 48 hpf, taken from the co-injected flt4 MO and FLT4 variant mRNA samples. One-way ANOVA comparing all samples to the flt4-depleted MO sample rescued by co-injection of human FLT4 expressing mRNA; *P < 0.05; ****P < 0.0001. (C) Histogram showing the percentage of embryos with d-loop, no loop/reduced heart size, or l-loop heart orientations.
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Full text @ Cardiovasc. Res.