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Fig. 6 Degarelix inhibits intracellular Mtb survival via autophagy. (a, b) BMDMs pretreated with degarelix (1 ?M), AGHS (100 ?M), BafA1 (100 nM), NAC (5 mM), Z-VAD (20 ?M), or 3-MA (5 mM) were infected with H37Rv (MOI = 2) at different times after which bacterial survival was calculated by dividing 24 h data by 3 h data (b). (c) Protein levels of P62 and LC3II in H37Rv-infected BMDMs pretreated with mock or degarelix (1 ?M).
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Full text @ Microb. Pathog.